The 29-year-old striker made his return to the Timão first-team against São Caetano over two weeks ago – after battling to lose weight in pre-season.
Corinthians had prepared a special training programme to help Adriano regain his fitness, but after his below-par performance against Santos on Sunday, the club have decided he must continue to improve his physical form this week.
The former Roma player is expected to return to action with Brasileiro champions against Guarani in the Campeonato Paulista on Saturday.
Corinthians likely line-up to face Nacional: Julio César; Alessandro (Edenílson), Chicão, Leandro Castán, Fábio Santos; Ralf, Paulinho, Danilo, Jorge Henrique (Alex); Emerson and Liedson.