After a 1-0 home defeat against fellow relegation candidates Atletico Mineiro on Wednesday night, Renato has walked away with the club second bottom and four points from safety.
He took over at Atletico at the beginning of July, shortly after resigning from the managerial post at Gremio.
In total, his Atletico Paranense record stood at four wins, five draws and five defeats during his brief spell as coach.